Micro-mark generally runs good deals on a box of 100 #11 blades. IIRC, I think they're Excel blades, actually. I can attest to what the guys are saying about wearing down the blades.
My first scratchbuild with cardstock was a house based on company housing in WVA. I did not even know about building with 100% cardstock at the time, so I naively built it with card as the base, roof and framing, and scale stripwood for the battens & porch as well as the windows. The chimbley is a metal casting. Walther's Goo worked well to join all these disparate parts together at major joints. Smaller joints, I think I used white glue or CA. It turned out fine and I am still happy with it, although it needs foundation pillars...eventually...
Anyway, I tried a Scalescenes kit (you can follow the progress in this forum, somewhere...I'm not going to track down the link right now, sorry) and after having built a solid cardstock kit, I like the multimedia method better! Card has its advantages and I think the skill is in deciding where it is best used alongside other materials.