Greg,
The easiest way to wire an HO railroad, is to have someone else do the wiring!
OK, maybe not. Wiring for DCC would be the easiest, in that you have two heavy gauge bus wires to carry power around the layout, and feeders, usually 20 gauge wire, soldered to the rails,
and the bus wires, about every 3'-4'.
Then, straight DC, with no blocks, and a single cab, is about the same.
DC, blocked, with multiple cabs, is complex. Lots of rotary switches to route the cabs to the blocks, and lots of gaps to isolate the blocks from each other.
The most complicated would be DC, blocked, with multiple cabs, and automated signalling.
Not sure what you're asking concerning brands, or type of equipment.
Pete